Table 1.
The top 30 DGEs via KEGG enrichment analysis.
| ID | Description | Significant | Annotated | Pvalue | Qvalue |
|---|---|---|---|---|---|
| ko05202 | Transcriptional misregulation in cancers | 70/1805 | 169/7736 | 1.00 × 10−7 | 3.00 × 10−5 |
| ko05034 | Alcoholism | 69/1805 | 180/7736 | 3.67 × 10−6 | 0.000551 |
| ko04151 | PI3K-Akt signaling pathway | 109/1805 | 337/7736 | 7.10 × 10−5 | 0.007097 |
| ko05206 | MicroRNAs in cancer | 52/1805 | 138/7736 | 9.58 × 10−5 | 0.007186 |
| ko00532 | Glycosaminoglycan biosynthesis—chondroitin sulfate/dermatan sulfate | 12/1805 | 20/7736 | 0.000469 | 0.027069 |
| ko04068 | FoxO signaling pathway | 46/1805 | 126/7736 | 0.000541 | 0.027069 |
| ko00270 | Cysteine and methionine metabolism | 21/1805 | 46/7736 | 0.000698 | 0.029904 |
| ko04971 | Gastric acid secretion | 29/1805 | 74/7736 | 0.001596 | 0.059848 |
| ko04015 | Rap1 signaling pathway | 67/1805 | 208/7736 | 0.001903 | 0.063443 |
| ko04115 | p53 signaling pathway | 26/1805 | 66/7736 | 0.002502 | 0.075074 |
| ko05219 | Bladder cancer | 18/1805 | 42/7736 | 0.003896 | 0.092958 |
| ko05224 | Breast cancer | 49/1805 | 148/7736 | 0.004009 | 0.092958 |
| ko04975 | Fat digestion and absorption | 17/1805 | 39/7736 | 0.004028 | 0.092958 |
| ko04512 | ECM-receptor interaction | 30/1805 | 84/7736 | 0.006771 | 0.140346 |
| ko04810 | Regulation of actin cytoskeleton | 65/1805 | 211/7736 | 0.007017 | 0.140346 |
| ko04024 | cAMP signaling pathway | 61/1805 | 197/7736 | 0.007824 | 0.144381 |
| ko05215 | Prostate cancer | 30/1805 | 85/7736 | 0.008182 | 0.144381 |
| ko04510 | Focal adhesion | 60/1805 | 195/7736 | 0.009586 | 0.154245 |
| ko04390 | Hippo signaling pathway | 47/1805 | 147/7736 | 0.009769 | 0.154245 |
| ko05200 | Pathways in cancer | 111/1805 | 392/7736 | 0.01089 | 0.161349 |
| ko00052 | Galactose metabolism | 14/1805 | 33/7736 | 0.011553 | 0.161349 |
| ko00900 | Terpenoid backbone biosynthesis | 10/1805 | 21/7736 | 0.012603 | 0.161349 |
| ko04391 | Hippo signaling pathway-fly | 25/1805 | 70/7736 | 0.01275 | 0.161349 |
| ko04066 | HIF-1 signaling pathway | 32/1805 | 95/7736 | 0.013676 | 0.161349 |
| ko04013 | MAPK signaling pathway-fly | 28/1805 | 81/7736 | 0.014076 | 0.161349 |
| ko05143 | African trypanosomiasis | 15/1805 | 37/7736 | 0.014586 | 0.161349 |
| ko04071 | Sphingolipid signaling pathway | 41/1805 | 128/7736 | 0.01462 | 0.161349 |
| ko04725 | Cholinergic synapse | 36/1805 | 110/7736 | 0.015059 | 0.161349 |
| ko04640 | Hematopoietic cell lineage | 28/1805 | 84/7736 | 0.023258 | 0.240598 |
| ko04320 | Dorso-ventral axis formation | 11/1805 | 26/7736 | 0.024647 | 0.245998 |