Table 3. Quantification of MSAs Uptake in the Blood, Liver, and Lung with Different DOF of ADIBO and Mannose Group Measured Using PET Imaging.
blood pool (% ID/g) | liver (% ID/g) | lung (% ID/g) | ||
---|---|---|---|---|
AD-Alb(6) | 0 h | 52.39 ± 2.46 | 15.77 ± 4.90 | 10.25 ± 2.99 |
2 h | 45.03 ± 1.39 | 19.40 ± 3.32 | 7.33 ± 0.97 | |
4 h | 36.64 ± 0.98 | 22.45 ± 1.50 | 5.21 ± 0.53 | |
24 h | 15.17 ± 1.56 | 16.00 ± 3.70 | 1.98 ± 0.08 | |
Man(2)-Alb | 0 h | 50.48 ± 2.30 | 15.48 ± 0.72 | 11.01 ± 2.1 |
2 h | 42.97 ± 2.67 | 19.18 ± 2.33 | 6.88 ± 0.69 | |
4 h | 30.47 ± 2.25 | 25.84 ± 0.67 | 5.11 ± 0.51 | |
24 h | 13.47 ± 4.03 | 25.30 ± 2.62 | 1.57 ± 0.05 | |
Man(4)-Alb | 0 h | 50.22 ± 1.15 | 17.20 ± 0.56 | 10.8 ± 1.15 |
2 h | 35.43 ± 2.81 | 22.87 ± 2.47 | 5.22 ± 0.35 | |
4 h | 20.93 ± 0.91 | 27.50 ± 1.57 | 4.87 ± 0.81 | |
24 h | 11.27 ± 2.87 | 22.83 ± 2.73 | 1.1 ± 0.08 | |
AD-Alb(11) | 0 h | 48.13 ± 2.19 | 19.23 ± 3.18 | 10.53 ± 3.33 |
2 h | 42.79 ± 2.24 | 23.23 ± 2.08 | 6.97 ± 0.78 | |
4 h | 33.67 ± 1.82 | 28.07 ± 1.46 | 5.01 ± 0.74 | |
24 h | 15.17 ± 1.56 | 25.67 ± 3.48 | 1.54 ± 0.1 | |
Man(6)-Alb | 0 h | 48.64 ± 4.27 | 22.50 ± 1.30 | 9.84 ± 2.54 |
2 h | 33.33 ± 2.25 | 41.87 ± 2.51 | 5.37 ± 0.85 | |
4 h | 20.63 ± 1.53 | 47.49 ± 2.36 | 4.22 ± 0.33 | |
24 h | 8.17 ± 2.20 | 28.27 ± 2.91 | 0.49 ± 0.04 | |
Man(8)-Alb | 0 h | 36.59 ± 1.39 | 29.63 ± 0.80 | 5.89 ± 1.22 |
2 h | 17.00 ± 1.35 | 47.67 ± 2.30 | 2.8 ± 0.35 | |
4 h | 12.13 ± 1.40 | 49.43 ± 2.05 | 2.3 ± 0.4 | |
24 h | 3.63 ± 0.60 | 46.13 ± 1.83 | 0.43 ± 0.02 |