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. 2022 Aug 9;16(8):12262–12275. doi: 10.1021/acsnano.2c03075

Table 3. Quantification of MSAs Uptake in the Blood, Liver, and Lung with Different DOF of ADIBO and Mannose Group Measured Using PET Imaging.

  blood pool (% ID/g) liver (% ID/g) lung (% ID/g)
AD-Alb(6) 0 h 52.39 ± 2.46 15.77 ± 4.90 10.25 ± 2.99
  2 h 45.03 ± 1.39 19.40 ± 3.32 7.33 ± 0.97
  4 h 36.64 ± 0.98 22.45 ± 1.50 5.21 ± 0.53
  24 h 15.17 ± 1.56 16.00 ± 3.70 1.98 ± 0.08
Man(2)-Alb 0 h 50.48 ± 2.30 15.48 ± 0.72 11.01 ± 2.1
  2 h 42.97 ± 2.67 19.18 ± 2.33 6.88 ± 0.69
  4 h 30.47 ± 2.25 25.84 ± 0.67 5.11 ± 0.51
  24 h 13.47 ± 4.03 25.30 ± 2.62 1.57 ± 0.05
Man(4)-Alb 0 h 50.22 ± 1.15 17.20 ± 0.56 10.8 ± 1.15
  2 h 35.43 ± 2.81 22.87 ± 2.47 5.22 ± 0.35
  4 h 20.93 ± 0.91 27.50 ± 1.57 4.87 ± 0.81
  24 h 11.27 ± 2.87 22.83 ± 2.73 1.1 ± 0.08
AD-Alb(11) 0 h 48.13 ± 2.19 19.23 ± 3.18 10.53 ± 3.33
  2 h 42.79 ± 2.24 23.23 ± 2.08 6.97 ± 0.78
  4 h 33.67 ± 1.82 28.07 ± 1.46 5.01 ± 0.74
  24 h 15.17 ± 1.56 25.67 ± 3.48 1.54 ± 0.1
Man(6)-Alb 0 h 48.64 ± 4.27 22.50 ± 1.30 9.84 ± 2.54
  2 h 33.33 ± 2.25 41.87 ± 2.51 5.37 ± 0.85
  4 h 20.63 ± 1.53 47.49 ± 2.36 4.22 ± 0.33
  24 h 8.17 ± 2.20 28.27 ± 2.91 0.49 ± 0.04
Man(8)-Alb 0 h 36.59 ± 1.39 29.63 ± 0.80 5.89 ± 1.22
  2 h 17.00 ± 1.35 47.67 ± 2.30 2.8 ± 0.35
  4 h 12.13 ± 1.40 49.43 ± 2.05 2.3 ± 0.4
  24 h 3.63 ± 0.60 46.13 ± 1.83 0.43 ± 0.02