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. 2022 Aug 8;12(8):732. doi: 10.3390/metabo12080732

Figure 2.

Figure 2

Treatment with ETG-5773 changes metabolic parameters in obese mice. (a) Body weight of DIO mice; (b) fasting blood glucose levels; (c) fasting serum insulin levels; * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001; (d) glucose tolerance test, # ETG-5773 vs. vehicle, * ETG-5773 vs. vehicle pair-fed, * or # p < 0.05, ** or ## p < 0.01, ns: non-significant, ANOVA, mean SD. Animals were treated orally twice a day with 15 mg/kg ETG-5773 or with the corresponding vehicle or vehicle in the pair-fed group, n = 12 vehicle and ETG-5773, n = 8 pair-fed.