Table 2.

Comparison of ETG-5773 with other known inhibitors. Compound structures are shown in Figure S1.

IC50 Measurements	ETG-5773	PF-06649298	BI01383298
HepG2 citrate uptake (human)	160 nM	50 µM	78 nM
HepG2 fatty acid synthesis	1 µM	39 µM	30 nM
HEK293 citrate uptake (mouse)	180 nM	6.6 µM	>50 µM