Figure 1.

Differentially expressed circRNAs in osteosarcoma cells and osteoblasts as well as enrichment analysis of related pathways. (A) Hierarchical cluster analysis of differentially expressed circRNAs. In the heatmap, red represents high expression, and green represents low expression. The columns represent cells, and the rows represent different circRNAs. (B) Volcano map showing differentially expressed circRNAs. The vertical line represents a multiple of 1.5, and the horizontal line indicates a p value equal to 0.05. (C-D) The KEGG database was used for pathway enrichment analysis of circRNAs. (E) Schematic illustration of hsa_circ_0087302 formation and the results of Sanger sequencing.