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. 2022 Aug 1;19(9):1377–1387. doi: 10.7150/ijms.69501

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Expression level of Wnt/β-catenin signaling pathway-related proteins after overexpression of hsa_circ_0087302. (A) The protein levels of β-catenin, cyclin D1, Dvl 2, Dvl 3, CD44, LRP 6, LEF 1, c-Myc and c-Jun were downregulated by lentiviral transduction in MG63 and U2OS cells, while the protein level of Axin was increased. GAPDH was used as a loading control. The bar chart shows the expression level of each protein in MG63 (B) and U2OS (C) cells compared to control cells. NC: negative control. Data represent the mean ± SD (n = 3) (*P < 0.05, **P < 0.01 and ***P < 0.001).