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. 2022 Aug 25;23(Suppl 6):558. doi: 10.1186/s12864-022-08796-y

Table 1.

Functional annotations of genes from the histidine metabolism subsystem

Name Functional role
HisZ ATP phosphoribosyltransferase (EC 2.4.2.17)
HisG ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
HisD Histidinol dehydrogenase (EC 1.1.1.23)
HisB Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
HisH Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
HisA Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
HisF Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
HisI Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)
HisE Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
HisC Histidinol-phosphate aminotransferase (EC 2.6.1.9)
HisJ Histidinol-phosphatase (EC 3.1.3.15)
HisR Histidine repressor, TrpR family
HisX Histidine ABC transporter, histidine-binding protein
HisY Histidine ABC transporter, permease protein
HisZ* Histidine ABC transporter, ATP-binding protein
YuiF Histidine permease YuiF

The HisZ component of histidine ABC transporter is marked with asterisk to distinguish it from eponymous enzyme