Table 1.

Summary of the use of functionalized MNPs for AMF-induced cancer therapy.

Types and Size of MNPs	Functionalizing Agents	Cancer Cells	Types of Study	AMF	Reference
Maghemite (γ-Fe2O3), ~5 nm	MS	A549, HeLa, Saos-2, HepG2	In vitro	100 kHz, 15,916 A m−1	[47]
Iron oxide (Fe3O4), 10–20 nm	Silica	L929, HeLa	In vitro	250 kHz, 26,659 A m−1	[48]
Manganese ferrite, ~50 nm	Silica-RITC, silica	HeLa	In vitro	33.3 A m−1	[49]
SPIONs, ~15 nm	Silica microbeads	Co112	In vitro, in vivo	141 kHz	[50]
Iron oxide magnetic nanorings, ~70 nm	Polyethylene glycol methyl ether	MCF-7	In vitro, in vivo	39,789 A m−1 400 kHz	[56]
Iron oxide magnetic nanorings ~70 nm	PD-L1, PEG	4T1	In vitro, in vivo	365 kHz, 30 kA m−1	[57]
Fe3O4 nanocube, ~30 nm	Chitosan oligosaccharide	A549	In vitro, in vivo	1 MHz, 208 A m−1	[58]
Iron oxide	PLGA	MDA-MB-231	In vitro, in vivo	513 kHz, 8 kW	[61]
Iron oxide	Polymethyl-methacrylate	MB-231	In vitro, in vivo	626 kHz, 28.6 A	[62]
Hexagonal cobalt and Manganese-doped MNPs, ~20 nm	Poly-ethylene glycol)-b-poly-caprolactone (PEG-PCL), SiNc	ES-2	In vitro, in vivo	420 kHz, 27 kA m−1	[63]
Mn–Zn ferrite magnetic nanocryastals, ~14 nm	Phospholipid-PEG, ICG, RGD	4T1	In vitro, in vivo	390 kHz, 2.6 kA m−1	[76]
Zn-doped iron oxide, ~15 nm	Au, ATAP	U87, MCF-7	In vitro	300 kHz, 5 kA m−1,	[77]
Ferric-oxide MNPs, ~70 nm	HER2 aptamers, dextran	SK-BR3, U87MG	In vitro	280 kHz, 300 A	[78]
Iron oxide	Calcium phosphate cements	MB-231	In vitro, in vivo	626 kHz, 28.6 A	[86]
Fe3O4 nanocube, ~20 nm	Serum albumin	U87MG	In vitro, in vivo	512 kHz, 10 kA m−1	[87]
Magnetite MNPs, ~8, 17, and 24 nm	Human-like collagen protein (HCP)	BHK-21	In vitro, in vivo	360 kHz, 44,564 A m−1	[88]
SPIONs, ~15 nm	Carboxyl-modified DNA20, MS, DOX	HeLa	In vitro	141 kHz	[51]
Magnetic MS, ~190 nm	NIPAM-co-MAA, MS, DOX	HeLa	In vitro	18 mT, 409 kHz	[52]
Maghemite, 16 nm	PEI/NIPAM, MS, soybean trypsin inhibitor	-	Drug release	24 kA m−1, 100 kHz	[53]
Iron oxide crystals, ~190 nm	Metal–organic framework-ZIF-90, PDA, DOX	HeLa	In vitro	18 mT, 490 kHz	[67]
Maghemite and magnetite magnetic nanorods, ~64 to 530 nm	Poly(ethyleneimine), Poly(sodium 4-styrenesulfonate), DOX	-	Drug release	10–20 kA m−1, 100–200 kHz	[68]
Mn-Zn ferrite MNPs, ~100 nm	PLA-b-poly(N-co-D), CPT	SK-OV-3, HepG2	In vitro	89.9 kA m−1, 114 kHz	[72]
Mn-Zn ferrite MNPs, ~100 nm	6sPCL-b-P(MEO2MA-co-OEGMA), DOX	Huh-7	In vitro, in vivo	89.9 kA m−1, 114 kHz	[73]
Citric-acid capped iron-oxide, ~12 nm	Liposomes, CET, CPT	U87MG	In vitro, in vivo	96 kHz, 60 A	[85]
Iron oxide nanocubes, 15 nm and 23 nm	Polycaprolactone nanofibers, DOX	HeLa, MCF-7	In vitro	110 kHz, 30 kA m−1	[91]