Table 3.
Clinicopathological characteristics based on the cut-off of CALLY index
| Variable | CALLY index ≥ 0.65 (n = 198) | CALLY index < 0.65 (n =81) | P |
|---|---|---|---|
| Sex | 0.763a | ||
| Men | 176 (70.7%) | 73 (29.3%) | |
| Women | 22 (73.3%) | 8 (26.7%) | |
| Age | 0.031a | ||
| < 65 | 150 (74.6%) | 51 (25.4%) | |
| ≥ 65 | 48 (61.5%) | 30 (38.5%) | |
| AJCC stage | 0.002a | ||
| I-II | 75 (83.3%) | 15 (16.7%) | |
| III-IV | 123 (65.0%) | 66 (35.0%) | |
| Tumor size (T classification) | <0.001a | ||
| T1-T2 | 100 (82.0%) | 22 (18.0%) | |
| T3-T4 | 98 (62.4%) | 59 (37.6%) | |
| Nodal metastasis (N classification) | 0.003a | ||
| N0 | 138 (77.1%) | 41 (22.9%) | |
| N1-N3 | 60 (60.0%) | 40 (40.0%) | |
| PNI | 0.415a | ||
| Absent | 151 (72.2%) | 58 (27.8%) | |
| Present | 47 (67.1%) | 23 (32.9%) | |
| ENE | <0.001a | ||
| Absent | 170 (75.9%) | 54 (24.1%) | |
| Present | 28 (50.9%) | 27 (49.1%) | |
| Cancer cell differentiation | 0.401a | ||
| W-D/M-D | 178 (71.8%) | 70 (28.2%) | |
| P-D | 20 (64.5%) | 11 (35.5%) | |
| Surgical margin | 0.253a | ||
| ≥ 5 mm | 150 (72.8%) | 56 (27.2%) | |
| < 5 mm | 48 (65.8%) | 25 (34.2%) | |
| DOI ≥ 10 mm | <0.001a | ||
| No | 117 (80.1%) | 29 (19.9%) | |
| Yes | 81 (60.9%) | 52 (39.1%) | |
| Tumor sites | 0.396a | ||
| Tongue | 84 (74.3%) | 29 (25.7%) | |
| Buccal mucosa | 61 (71.8%) | 24 (28.2%) | |
| Other | 53 (65.4%) | 28 (34.6%) | |
| Personal habits | 0.673a | ||
| No exposure | 24 (75.0%) | 8 (25.0%) | |
| One exposure | 14 (77.8%) | 4 (22.2%) | |
| Two or all exposure | 160 (69.9%) | 69 (30.1%) | |
| Treatment | 0.001a | ||
| Surgery only | 103 (76.9%) | 31 (23.1%) | |
| Surgery + RT | 33 (84.6%) | 6 (15.4%) | |
| Surgery + CRT | 62 (58.5%) | 44 (41.5%) | |
| CCI | 0.091a | ||
| 0 | 111 (76.6%) | 34 (23.4%) | |
| 1 | 52 (63.4%) | 30 (36.6%) | |
| ≥ 2 | 35 (67.3%) | 17 (32.7%) | |
| Laboratory results | |||
| Albumin(g/dL), median (IQR) | 4.55 (4.32-4.72) | 4.06 (3.59-4.41) | <0.001b |
| WBC (X103/μL), median (IQR) | 7.45 (6.18-9.20) | 8.20 (6.55-10.85) | 0.055b |
| Neutrophil (X103/μL), median (IQR) | 4.54 (3.58-6.03) | 5.48 (3.70-7.60) | 0.007b |
| Lymphocyte (X103/μL), median (IQR) | 2.09 (1.66-2.65) | 1.87 (1.43-2.34) | 0.001b |
| CRP (mg/dL), median (IQR) | 1.85 (0.92-4.16) | 3.65 (1.88-7.18) | <0.001b |
| Survival in months, median (IQR) | 50.00 (31.75-70.00) | 26.50 (10.75-66.50) | <0.001b |
athe Chi-square test. bthe Mann-Whitney U test.