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. 2022 Aug 26;22:224. doi: 10.1186/s12906-022-03701-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — ROS production (a, b) and viability (c) of the ARPE-19 cells. a, b: The ImageJ software was used to measure the intensity of the fluorescence. The rate of production of ROS in the LD group (84.94 ± 3.29%) increased by 45.92% (P < 0.001) compared with that in the control group (58.21 ± 6.46%); the rate in the LC (76.62 ± 4.40%) and HC (61.56 ± 2.02%) groups decreased by 10.5% (P < 0.05) and 27.53% (P < 0.0001), respectively, compared with that in the LD group. c: After treatment with the chrysanthemum extract before light damage, the cell viability rate in the LC and HC groups increased to 69.22 and 76.04%, respectively, compared with that in the LD group (P < 0.05 and P < 0.001); the data were analysed using one way-ANOVA. *P < 0.05, **P < 0.01, ***P < 0.0001