Table 1.
Nutritional parameters and laboratory analytes of the dogs depending on the group (G) they belong to (CRT = control; TRT = treated), time (T), and their interaction (G × T).
| Group (G) | Time (T) | SEM | p-Value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CTR | TRT | T0 | T1 | T2 | T3 | T4 | T5 | G | T | G | T | G × T | |
| Laboratory analytes (unit) | |||||||||||||
| pH | 6.51 | 6.50 | 6.50 | 6.54 | 6.50 | 6.52 | 6.46 | 6.50 | 0.06 | 0.05 | 0.982 | 0.152 | 0.161 |
| Calprotectin (µg/g) | 5.95 | 5.57 | 5.99 ab | 6.04 a | 5.94 b | 5.63 cd | 5.64 c | 5.32 d | 0.85 | 0.60 | 0.753 | <0.001 | 0.108 |
| Lactoferrin (µg/g) | 1.53 | 1.32 | 1.45 | 1.45 | 1.31 | 1.38 | 1.49 | 1.44 | 0.22 | 0.16 | 0.489 | 0.260 | 0.330 |
| Zonulin (ng/mL) | 52.51 | 50.36 | 49.58 | 52.35 | 49.84 | 53.79 | 50.18 | 52.96 | 0.77 | 1.16 | 0.046 | 0.250 | 0.710 |
| Cortisol (pg/mg) | 0.61 | 0.55 | 0.60 | 0.65 | 0.57 | 0.60 | 0.53 | 0.54 | 0.02 | 0.02 | 0.090 | 0.100 | <0.001 |
| Immunoglobulin A (mg/g) | 47.71 | 48.17 | 48.87 | 48.68 | 48.33 | 47.40 | 47.66 | 46.75 | 1.70 | 1.23 | 0.849 | 0.100 | 0.116 |
| Short chain fatty acids (μmol/g) | 143.56 | 146.96 | 148.11 | 145.94 | 139.55 | 146.24 | 145.04 | 146.77 | 21.39 | 15.54 | 0.912 | 0.112 | 0.180 |
| Indole/skatole (μmol/g) | 1.76 | 1.60 | 1.67 | 1.73 | 1.63 | 1.66 | 1.69 | 1.68 | 0.04 | 0.06 | <0.001 | 0.937 | 0.001 |
Means with superscript letters (a, b, c, d) identify significant differences among the sampling times (p < 0.05).