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. 2022 Aug 9;12(8):735. doi: 10.3390/metabo12080735

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Relationship between cecal, plasma and amniotic fluid SCFAs in pregnant dams on nicotine. In (A), a positive correlation between cecal and circulating (plasma) acetate, propionate, butyrate and hexanoic acid was observed in pregnant control (PREG CON) dams alone. In (B), a positive correlation between circulating (plasma) and amniotic fluid levels of all measured SCFAs was observed in some samples from PREG CON dams. Linear regression analysis was performed, * p < 0.05, ** p < 0.01, *** p < 0.001 from zero; n = 8–10 samples per group.

Relationship between cecal, plasma and amniotic fluid SCFAs in pregnant dams on nicotine. In (A), a positive correlation between cecal and circulating (plasma) acetate, propionate, butyrate and hexanoic acid was observed in pregnant control (PREG CON) dams alone. In (B), a positive correlation between circulating (plasma) and amniotic fluid levels of all measured SCFAs was observed in some samples from PREG CON dams. Linear regression analysis was performed, * p < 0.05, ** p < 0.01, *** p < 0.001 from zero; n = 8–10 samples per group.