Table 1.
Individual exposure of AFB1 and FB1 effects on zebrafish larvae endpoints.
| Survival | Hatching | Morphology | ||||||
|---|---|---|---|---|---|---|---|---|
| 24 h | 48 h | 72 h | 96 h | 48 h | 72 h | 96 h | 96 h | |
| CTRL | 98.33 ± 0.88 | 98.00 ± 1 | 97.67 ± 1.20 | 97.67 ± 1.20 | 22.67 ± 1.45 | 100 ± 0 | 100 ± 0 | - |
| AFB1 0.01 mg/kg | 98.33 ± 0.88 | 97.33 ± 0.88 | 97.00 ± 1 | 97.00 ± 1 | 22.33 ± 1.45 | 99.67 ± 0.33 | 99.67 ± 0.33 | - |
| AFB1 0.05 mg/kg | 98.33 ± 0.88 | 97.67 ± 0.66 | 97.33 ± 0.88 | 97.33 ± 0.88 | 22 ± 1.73 | 99 ± 0.33 | 99.3 ± 0.57 | - |
| AFB1 0.1 mg/kg | 99.00 ± 0.57 | 95.00 ± 0.57 ** | 86.33 ± 0.88 *** | 83.00 ± 1.15 *** | 18.67 ± 1.76 ** | 90.00 ± 0.57 *** | 92.00 ± 0.57 *** | SC, PE |
| FB1 0.1 mg/kg | 98.33 ± 0.88 | 98.00 ± 1 | 97.67 ± 1.20 | 97.67 ± 1.20 | 22.33 ± 1.45 | 99.67 ± 0.33 | 99.67± 0.33 | - |
| FB1 0.5 mg/kg | 98.33 ± 0.88 | 96.00 ± 0.57 | 93.00 ± 01.52 *** | 90.33 ± 1.20 *** | 3 ± 1.15 *** | 86.00 ± 1.15 *** | 94 ± 1.15 *** | SC |
| FB1 1 mg/kg | 99.00 ± 0.57 | 95.00 ± 0.57 ** | 88.33 ± 1.45 *** | 83.33 ± 0.88 *** | 2.33 ± 0.33 *** | 80.67 ± 1.52 *** | 93.00 ± 1.73 *** | SC, PE, YE |
Lethal endpoint at 96 hpf after exposure of different concentration of AFB1 (0.01, 0.05, and 0.1 mg/kg) and FB1 (0.1, 0.5, and 1 mg/kg). Survival rate, hatching rate, and morphological alteration (SC = Scoliosis, PE = Pericardial Edema, YE = Yolk Sac Edema) were observed and reported as means ± SEM (standard error of mean); ** p < 0.01; *** p < 0.001 versus CTRL.