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. 2022 Aug 12;27(16):5154. doi: 10.3390/molecules27165154

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Resveratrol reduced oxidative injury in AA rats after injecting FCA 20 days, treated with 5 mg/kg, 15 mg/kg, 45 mg/kg resveratrol and 200 mg/kg N-acetyl-L-cysteine (NAC) for 12 days by continuous intragastric administration. (A) Swelling degree of the paw in SD rats after intragastric administration. (B) Lipoperoxide levels in the serum from six groups rats. (C) SOD activity in serum from six groups of rats. (D) Antioxidant capacity in serum from six groups of rats. (E) The ratio of glutathione peroxidase and glutathione reductase in serum from six groups of rats. (F) HE staining of knee joint in AA rats after administration resveratrol. Values are the means ± SD of at least three independent experiments. * p < 0.05 versus control; ^# p < 0.05, ^## p < 0.01 versus model. (Reproduced with permission from [82]).