Table 2.
Composition and physicochemical characteristics of biorelevant FeSSIF-V2-like media for dissolution experiments simulating the small intestine environment in a mouse in a fed state.
| Reagents | FeSSIF-V2-like |
|---|---|
| Lecithin (mM) | 2 |
| Sodium taurocholate (mM) | 10 |
| Glyceryl monooleate (mM) | 5 |
| Sodium monooleate (mM) | 0.8 |
| Sodium chloride (mM) | 25.0 |
| Potassium citrate (mM) | 10 |
| Potassium phosphate (mM) | 4.3 |
| Sodium hydroxide (mM) | 10 |
| Physicochemical characteristics | |
| Buffer capacity (mM/∆pH) | 25.2 |
| Osmolality (mOsm/kg) | 389 |
| pH | 4.8 |