Table 6.

Trapping parameters.

	B	BR	BT	Cell Number
10 µM REL-1017	83.8 ± 1.2 ****	71.8 ± 1.1 ***	85.9 ± 1.9	13
1 µM (±)-ketamine	74.0 ± 1.2	64.1 ± 1.3	86.7 ± 1.8	11

Experiments were conducted in whole-cell patch-clamp electrophysiology at a holding potential of −70 mV. Trapped block (B_T) results were similar for 10 µM REL-1017 and 1 µM (±)-ketamine, although their initial block (B) and residual block (B_R) were significantly different. Experiments were carried out as exemplified in Figure 5. Table data are mean ± SEM. Data passing normality (Shapiro–Wilk) test were analyzed with two-tailed unpaired T test. **** is p < 0.0001; *** is p < 0.001.