Figure 5.

Mean with 95 percent confidence intervals over the course of the study for clinical chemistry parameters. Confidence interval was not plotted for sample size less than 3. Unless otherwise noted, values were log-transformed, and the geometric mean is displayed. Terminal (T)—Terminal data collected from animals that met euthanasia criteria (unscheduled euthanasia) were combined and reported as a single time point. On Day 9, Animal 584 values for ALT, BA, and CRP were not able to be detected (likely as a result of being too high, out of range) and thus are not graphed. (a) ALT; (b) GGT; (c) BA; (d) TBIL; (e) ALB—this parameter was not log-transformed, arithmetic mean displayed; (f) CRP.