Table 2.
Viral load in serum as determined by plaque assay (plaque-forming units/mL).
| Animal ID | Group Description | Day of Death | Day 0 | Day 2 | Day 3 | Day 5 | Day 7 | Day 9 | Day 11 | Day 13 | Day 14 | Terminal * |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 594 | SE | Day 2 (S) | BDL | BDL | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - |
| 597 | SE | Day 2 (S) | BDL | 1.00 × 101 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | - |
| 585 | SE | Day 3 (S) | BDL | N/A | BDL | N/A | N/A | N/A | N/A | N/A | N/A | - |
| 605 | SE | Day 3 (S) | BDL | N/A | 6.13 × 102 | N/A | N/A | N/A | N/A | N/A | N/A | - |
| 592 | SE | Day 5 (S) | BDL | N/A | 7.50 × 100 | 5.50 × 103 | N/A | N/A | N/A | N/A | N/A | - |
| 602 | SE | Day 5 (S) | BDL | N/A | 1.25 × 101 | 1.33 × 106 | N/A | N/A | N/A | N/A | N/A | - |
| 589 | SE | Day 7 (S) | BDL | N/A | 3.75 × 101 | 1.08 × 106 | 3.40 × 107 | N/A | N/A | N/A | N/A | - |
| 603 | SE | Day 7 (S) | BDL | N/A | BDL | 2.00 × 104 | 7.75 × 107 | N/A | N/A | N/A | N/A | - |
| 584 | SE | Day 9 (S) | BDL | N/A | BDL | ND | 1.69 × 106 | 7.50 × 107 | N/A | N/A | N/A | - |
| 595 | SE | Day 9 ¶ | BDL | N/A | BDL | 2.75 × 103 | 1.06 × 108 | N/A | N/A | N/A | N/A | FDIC |
| 591 | SP-TK | Day 7 (US) | BDL | N/A | 2.50 × 101 | 7.13 × 105 | 1.31 × 108 | N/A | N/A | N/A | N/A | ND |
| 588 | SP-TK | Day 8 (US) | BDL | N/A | 1.15 × 102 | 2.03 × 105 | 2.43 × 107 | N/A | N/A | N/A | N/A | 2.70 × 107 |
| 593 | SP-TK | Day 8 (US) | BDL | N/A | UD | 1.26 × 106 | 3.00 × 108 | N/A | N/A | N/A | N/A | 3.09 × 108 |
| 596 | SP-TK | Day 8 (US) | BDL | N/A | 1.00 × 101 | 1.03 × 106 | 1.55 × 108 | N/A | N/A | N/A | N/A | ND |
| 601 | SP-TK | Day 8 (US) | BDL | N/A | 1.80 × 102 | 1.95 × 107 | 3.45 × 107 | N/A | N/A | N/A | N/A | FDIC |
| 604 | SP-TK | Day 8 (US) | BDL | N/A | 1.50 × 101 | 2.43 × 107 | 8.88 × 107 | N/A | N/A | N/A | N/A | FDIC |
| 587 | SP-TK | Day 9 (US) | BDL | N/A | 9.00 × 101 | 1.38 × 105 | 3.54 × 107 | FDIC | N/A | N/A | N/A | FDIC |
| 600 | SP-TK | Day 9 (US) | BDL | N/A | BDL | 1.10 × 105 | 3.24 × 107 | FDIC | N/A | N/A | N/A | FDIC |
SP-TK—Survival and Clinical Pathology Time Kinetics; SE—Serial Sample and Euthanasia; BDL—below detection limit; UD—titer undetermined after repeat; FDIC—found dead in cage; S—Scheduled; US—Unscheduled; ¶ Animal was scheduled for euthanasia on Day 9 but was FDIC; ND—no data, sample not available; * Data from unscheduled moribund euthanasia occurring outside a usual collection time point.