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. 2022 Jul 28;14(8):1653. doi: 10.3390/v14081653

Figure 2.

Figure 2

Kinetics of antigenemia since the onset of symptoms in non-severe and severe patients. The grey dotted lines correspond to the positivity cut-off of each antigen assay, as found by ROC curve analyses. The black dotted line corresponds to the positivity cut-off of the iFlash assay, as declared by the manufacturer. The red dotted lines correspond to the severity cut-off of each antigen assay, as found by the ROC curve analyses for the day 2–day 14 window. Only patients with symptoms and negative for SARS-CoV-2 Spike IgG directed against the spike protein were included in this kinetics representation.