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. 2022 Jul 28;14(8):1653. doi: 10.3390/v14081653

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Positive and negative SARS-CoV-2 Spike IgG results in serum according to antigenemia. The grey dotted lines on the Y-axis correspond to the positivity cut-off of each antigen assay, as found by ROC curve analyses. The black dotted line on the Y-axis of the iFlash panel represents the cut-off specified by the manufacturer. (B) Linear regression of antigenemia obtained with the two antigen assays versus the amount of SARS-CoV-2 Spike IgG. The grey dotted line on the X-axis represents the positivity cut-off for IgG directed against the spike protein.