TABLE 3.
Summary of IOP, Reduction in IOP From Baseline and Number of IOP-lowering Medications for Each Study Visit
No. Participants Analyzed | IOP (mm Hg) | No. IOP-lowering Medications | IOP Reduction From Baseline (mm Hg) [P] | |||||
---|---|---|---|---|---|---|---|---|
Visit | SGDD | CPC | SGDD | CPC | SGDD | CPC | SGDD | CPC |
Baseline | 22 | 20 | 27.6 (±8.7) | 26.2 (±9.7) | 3.0 (±1.0) | 3.3 (±1.1) | — | — |
[15–46] | [13–55] | [0–4] | [1–5] | |||||
Week 1 | 22 | 19 | 17.7 (±10.2) | 12.7 (±7.3) | 1.7* (±1.6) | 2.8* (±1.5) | 9.9 (±14.4) | 13.7 (±7.4) |
[3–46] | [5–40] | [0–4] | [0–4] | [−23.5 to 39] | [−1.5 to 28.5] | |||
[0.004] | [<0.001] | |||||||
Month 1 | 22 | 18 | 17.4 (±9.0) | 13.2 (±6.2) | 1.6 (±1.4) | 2.2 (±1.3) | 10.1 (±11.7) | 12.9 (±9.8) |
[5–36] | [3–27.5] | [0–4] | [0–4] | [−14.5 to 30.5] | [−5 to 31] | |||
[0.001] | [<0.001] | |||||||
Month 3 | 21 | 18 | 15.4 (±6.6) | 16.0 (±7.5) | 1.4 (±1.4) | 2.1 (±1.4) | 11.5 (±9.3) | 10.1 (±7.1) |
[3–31] | [9–42] | [0–4] | [0–4] | [−1.5 to 31] | [−4.5 to 25] | |||
[<0.001] | [<0.001] | |||||||
Month 6 | 19 | 19 | 13.5 (±4.2) | 13.6 (±4.0) | 1.9 (±1.3) | 2.2 (±1.2) | 13.7 (±9.1) | 12.8 (±10.7) |
[4–20] | [5–21] | [0–4] | [0–4] | [2.5–34.5] | [−4.5 to 34] | |||
[<0.001] | [<0.001] | |||||||
Month 12 | 16 | 16 | 14.9 (±4.5) | 13.9 (±6.3) | 2.1 (±1.3) | 1.7 (±1.4) | 11.6 (±7.6) | 12.3 (±7.9) |
[8–24] | [8.5–34.5] | [0–4] | [0–4] | [−3 to 25] | [−5 to 27.5] | |||
[<0.001] | [<0.001] | |||||||
Year 2 | 6 | 9 | 14.8 (±6.5) | 14.3 (±4.7) | 1.5 (±1.6) | 1.4 (±1.0) | 16.0 (±6.3) | 13.11 (±10.6) |
[6.3–25] | [9–24.5] | [0–3] | [0–3] | [7–24] | [3.5–30.5] | |||
[0.002] | [0.006] | |||||||
Year 3 | 6 | 5 | 14.6 (±4.4) | 12.8 (±3.0) | 2.2 (±1.7) | 2.2 (±0.8) | 18.5 (±8.1) | 14.50 (±8.8) |
[9.5–22] | [10–16] | [0–4] | [1–3] | [5–28] | [7–28.5] | |||
[0.003] | [0.02] |
For P<0.05.
For P<0.01.
For P<0.001 Obtained from 2-sample t test or Fisher Exact test for comparing between groups.
All data are presented as mean (±SD) [range].
P-value obtained from paired t test for within each group.
CPC indicates cyclophotocoagulation; IOP, intraocular pressure; SGDD, second glaucoma drainage device.