TABLE 2.
Risk (odds) of cardiovascular adverse event based on different levels of human plasma extracellular vesicle markers using conditional logistic regression models
| Extracellular vesicle marker | Matched analysis OR (95% CI)a | P value | Adjusted OR (95% CI)b | P value |
| Mode (per nm) | 0.97 (0.94–1.00) | 0.053 | 0.97 (0.94–1.01) | 0.158 |
| CD14 (log2 objects/ml) | 3.74 (1.12–12.49) | 0.032 | 4.41 (0.94–20.76) | 0.060 |
| CD146 (log2 objects/ml) | 1.41 (0.81–2.48) | 0.228 | 1.61 (0.69–3.79) | 0.273 |
| CD14/CD41 (log2 objects/ml) | 1.39 (0.93–2.06) | 0.104 | 1.49 (0.84–2.63) | 0.172 |
CI, confidence interval.
a
Matched analysis: matched for age and duration of treatment.
b
Matched analysis, adjusted for sex, baseline SBP, treatment allocation, and smoking status.