Descriptive features |
Inattention, impairment of immediate memory |
Memory impairments, plus impairments in multiple other cognitive domains |
Behavioural disorder, mental rigidity, distractibility |
Fluctuating cognition with variations in attention and alertness |
Abrupt deterioration or stepwise progression of cognitive deficits; mood and personality changes |
Onset |
Acute, episodic |
Insidious |
Insidious |
Insidious |
Insidious, abrupt or stepwise |
Duration |
Hours to months |
Months to years |
Months to years |
Months to years |
Months to years |
Course |
Fluctuating, might be worse at night and on waking |
Chronic, progressive |
Chronic, progressive |
Chronic, progressive |
Chronic, progressive |
Alertness |
Altered |
Normal |
Normal |
Fluctuates |
Normal |
Reversibility |
Usually |
No |
No |
No |
No |
Attention |
Impaired by definition |
Usually, normal, but might be impaired in later stages |
Might be persistently impaired and early feature |
Fluctuates |
Might be persistently impaired and early feature |
Orientation |
Fluctuates |
Not oriented |
Typically intact |
Variable |
Variable |
Speech |
Incoherent speech |
Word-finding difficulties |
Altered speech output; stereotypy of speech; echolalia; perseveration; mutism |
Hypophonic speech |
– |
Thought |
Disorganized and disconnected thoughts, for example, ‘flight of ideas’ |
Difficulty with abstract thinking |
Poor judgement; impulsivity |
– |
Abnormal executive function, including mental rigidity and poor insight and judgment |
Perception |
Distorted: illusions, delusions and/or hallucinations (often visual, tactile or poorly formed) |
Delusions of theft or persecution, more common in later stages; hallucinations (auditory, distinct) uncommon |
Delusions might be paranoid, religious or bizarre in nature |
Visual hallucinations are recurrent and typically well-formed and detailed (that is, animals or children); delusions are common |
Delusions more common in later stages |
Psychomotor changes |
Frequent |
Inconsistent |
Hyperorality; utilization behaviour |
Parkinsonism |
Psychomotor retardation |
Agitation |
Occurs with delirium symptoms, throughout the day |
Might occur with sundowning or when resisting activities of daily living |
Common |
Variable |
Variable |
Sleep–wake cycle |
Often reversed |
Might be fragmented but circadian rhythmicity retained |
Severely fragmented |
REM sleep behaviour disorder |
Sleep disturbances are common |