Table 6.
DNA damage effect of N. cataria extracts on liver cells of albino Wistar rats.
Groups | rtail Moment | % rDNA in Tail | rtail Length |
---|---|---|---|
I | 1.44 ± 0.32 a† | 3.08 ± 0.40 † | 2.60 ± 0.73 † |
II | 16.51 ± 1.23 * | 10.80 ± 1.50 * | 24.65 ± 1.03 * |
III | 1.64 ± 0.63 † | 3.72 ± 0.94 † | 2.90 ± 0.86 † |
IV | 2.99 ± 0.6 *† | 4.22 ± 0.54 *† | 3.17 ± 0.63 † |
V | 4.72 ± 0.3 *† | 7.62 ± 0.34 *† | 5.6 ± 0.82 *† |
a Data are presented as the means ± SEM obtained from three independent experiments; n = 25 rats; 5 rats per group. I, Control group, animals treated orally for five days with distilled water and then intraperitoneally (i.p.) injected with 1 mL/kg body weight (bwt) in olive oil; II, CCl4 1 mL/kg i.p.; III, N. cataria FME 200 mg/kg;, IV, N. cataria LME 200 mg/kg; V, N. cataria SME 200 mg/kg; * p < 0.05 when compared with the negative control group; † p < 0.05 when compared with the positive control group.