Table 3.
Amino acid mutations observed in the Spike protein of the Italian human sequences available through GISAID (https://www.gisaid.org/, accessed on 30 May 2022) in 2020–2021.
| Spike Protein-Amino Acid Mutations | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Collection date | Number of sequences | L216H | S477N | N501Y | D614G | P681H | Y453F | Mink Cluster V | Pango lin | |
| Human sequence | 1 August 2020 | 1 | no | no | no | yes | no | no | no | B.1 |
| Mink sequence | 17 August 2020 | 1 | yes | no | yes | yes | yes | no | no | B.1.1 |
| Mink sequence | 29 October 2020 | 1 | no | yes | no | yes | no | no | no | B.1.160 |
| Human sequences from Italy available in GISAID | 2020 | 5.634 | 0% | 230 (4.1%) | 173 (3.1%) | 5.343 (94.8%) | 180 (3.2%) | no | no | |
| Human sequences from Italy available in GISAID | 2021 | 90.147 | 0% | 2.748 (3%) | 33.363 (37%) | 86.701 (96.2%) | 32.622 (36.2%) | 3 (0.003%) | no | |