Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Kinase selectivity profile of 10b and 10d.
| Kinase | IC50 (nM) |
|
|---|---|---|
| 10b | 10d | |
| TEK | >2000 | >2000 |
| SYK | 1120 ± 22 | 870 ± 31 |
| EPHB2 | >2000 | >2000 |
| ABL1 | >2000 | >2000 |
| LCK | >2000 | >2000 |
| CLK1 | 1069 ± 54 | 798 ± 19 |
| ROCK1 | >2000 | >2000 |
| PKC | >2000 | >2000 |
| AKT1 | 816 ± 38 | 702 ± 24 |
| CDK1 | 310 ± 12 | 245 ± 7 |
| CDK5 | 1136 ± 20 | 993 ± 15 |
