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Cytotoxic effect of 10b and 10d towards human non-tumorigenic lung WI-38 cells and mean tumour selectivity index (S. I.) (WI-38/A549 and H441).
| Compound | IC50 (µM) ± SEM |
Mean tumour selectivity | ||
|---|---|---|---|---|
| WI-38 | A549 | H441 | ||
| 10b | 72.4 ± 7.2 | 4.2 ± 0.8 | 4.7 ± 0.1 | 16.1 |
| 10d | 51.4 ± 3.5 | 2.9 ± 0.2 | 3.8 ± 0.5 | 15.3 |
