Table 7.
Inhibitory activity of thiazolyl-pyrazoline derivatives 10 b and 10d against EGFR-mutated NSCLC cell lines.
| Compound | IC50 (µM) |
|
|---|---|---|
| NCI-H1650 | NCI-H1975 | |
| 10b | 5.7 ± 0.5 | 6.2 ± 0.9 |
| 10d | 3.5 ± 0.2 | 4.4 ± 0.6 |
| Gefitinib | >20 | >20 |
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