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. 2022 Aug 12;14:919143. doi: 10.3389/fnagi.2022.919143

TABLE 4.

Neuropsychological test results.

NC (N = 20) MCI (N = 21) AD (N = 20) F p
MMSE 28.10 ± 0.79 25.10 ± 1.48* 15.60 ± 3.07*# 211.247 <0.001
MoCA 27.70 ± 0.66 21.10 ± 3.08* 10.35 ± 4.10*# 172.309 <0.001
HDSR 28.60 ± 0.50 24.76 ± 1.09* 12.60 ± 3.63*# 290.460 <0.001
CDR 0.00 ± 0.00 0.50 ± 0.00 1.50 ± 0.58*# 104.224 <0.001
DST 12.25 ± 0.72 11.43 ± 1.75 9.60 ± 0.60*# 27.516 <0.001
VFT 37.95 ± 3.40 30.71 ± 5.98* 19.65 ± 7.93*# 46.331 <0.001
FAB 17.70 ± 0.57 15.95 ± 2.13* 9.70 ± 3.21*# 70.175 <0.001
TMTA (s) 58.56 ± 7.64 72.93 ± 22.85 132.73 ± 42.84*# 38.806 <0.001
RAVLT RAVLT immediate 38.80 ± 1.70 30.52 ± 5.51* 10.00 ± 3.84*# 271.120 <0.001
RAVLT short 10.25 ± 0.97 4.90 ± 2.63* 0.05 ± 0.22*# 192.932 <0.001
RAVLT long 9.00 ± 1.17 3.10 ± 2.70* 0.00 ± 0.00*# 141.308 <0.001
RAVLT recognition 13.60 ± 1.35 10.57 ± 2.01* 0.65 ± 2.00*# 277.294 <0.001
NPI-Q NPI-Q1 0.00 ± 0.00 1.48 ± 5.27 11.65 ± 16.78*# 7.943 0.001
NPI-Q2 0.00 ± 0.00 1.00 ± 3.00 7.20 ± 9.69*# 9.033 <0.001
HAMA 1.55 ± 4.84 11.29 ± 8.30* 9.70 ± 7.21* 11.403 <0.001
HAMD 1.30 ± 4.00 11.19 ± 10.68* 13.55 ± 7.57* 13.385 <0.001
ADL 20.00 ± 0.00 20.24 ± 0.63 31.95 ± 8.34*# 40.996 <0.001

NC, normal cognition; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MMSE, mini-mental state examination; MoCA, Montreal cognitive assessment scale; HDSR, Hasegawa dementia scale revised; CDR, clinical dementia rating scale; DST, digit span test; VFT, verbal fluency test; FAB, frontal assessment battery; TMTA, trail making test A; RAVLT, Rey auditory verbal learning test (immediate recall/short-term delayed recall/long-term delayed recall/recognition); NPI-Q, neuropsychiatric inventory-questionnaire (NPI-Q1: the score of patient, NPI-Q2: the score of caregiver); HAMA, Hamilton anxiety scale; HAMD, Hamilton depression scale; ADL, activity of daily living scale. *p < 0.05 vs. NC group; #p < 0.05 vs. MCI group.