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. 2022 Aug 12;14:919143. doi: 10.3389/fnagi.2022.919143

TABLE 6.

Pearson’s correlation analysis between MD and neuropsychological test.

MD F P O T Pc H
MMSE −0.493** −0.348** −0.466** −0.373** 0.722** −0.504**
MoCA −0.432** −0.328** −0.445** −0.365** 0.687** −0.477**
HDSR −0.436** −0.360** −0.431** −0.365** 0.713** −0.528**
CDR 0.336** 0.326* 0.402** 0.355** 0.714** 0.539**
DST −0.273* −0.359** −0.345** −0.500** −0.481** −0.456**
VFT −0.345** −0.282* −0.312* −0.451** −0.542** −0.288*
FAB −0.371** −0.386** −0.405** −0.323* 0.616** −0.432**
TMTA 0.363** 0.378** 0.258* 0.470** 0.333**
RAVLT immediate −0.505** −0.395** −0.451** −0.389** 0.700** −0.501**
RAVLT short −0.492** −0.447** −0.390** −0.359** 0.680** −0.485**
RAVLT long −0.443** −0.417** −0.315* −0.368** 0.624** −0.417**
RAVLT recognition −0.451** −0.407** −0.421** −0.409** 0.663** −0.551**
NPI-Q1 0.406**
NPI-Q2 0.361**
HAMA 0.411**
HAMD 0.407** 0.423**
ADL 0.368** 0.300* 0.456** 0.392**

MD, mean diffusion; F, frontal lobe; P, parietal lobe; O, occipital lobe; T, temporal lobe; Pc, precuneus; H, hippocampus; MMSE, mini-mental state examination; MoCA, Montreal cognitive assessment scale; HDSR, Hasegawa dementia scale revised; CDR, clinical dementia rating scale; DST, digit span test; VFT, verbal fluency test; FAB, frontal assessment battery; TMTA, trail making test A; RAVLT, Rey auditory verbal learning test (immediate recall/short-term delayed recall/long-term delayed recall/recognition); NPI-Q, neuropsychiatric inventory-questionnaire (NPI-Q1: the score of patient, NPI-Q2: the score of caregiver); HAMA, Hamilton anxiety scale; HAMD, Hamilton depression scale; ADL, activity of daily living scale. *p < 0.05, **p < 0.01. Bold data (0.6–0.8), indicating high-intensity correlation.