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. 2022 Aug 12;14:919143. doi: 10.3389/fnagi.2022.919143

TABLE 7.

Pearson’s correlation analysis between MD and neuropsychological test.

MD SCC GCC PIC LN CR CS
MMSE −0.314* −0.357** −0.378** −0.370** −0.479**
MoCA −0.418** −0.307* −0.361** −0.477**
HDSR −0.262* −0.397** −0.396** −0.391** −0.488**
CDR 0.298* 0.333** 0.347** 0.512**
DST −0.254* −0.500** −0.341**
VFT −0.515** −0.385** −0.401**
FAB −0.350** −0.325* −0.381** −0.433**
TMTA 0.356** 0.358** 0.434** 0.362**
RAVLT immediate −0.281* −0.383** −0.299* −0.499** −0.549**
RAVLT short −0.273* −0.382** −0.473** −0.516**
RAVLT long −0.385** −0.483** −0.489**
RAVLT recognition −0.446** −0.271* −0.467** −0.480**
NPI-Q1 0.319* 0.326*
NPI-Q2 0.281* 0.306*
HAMA 0.394**
HAMD 0.401**
ADL 0.380** 0.381**

MD, mean diffusion; SCC, splenium of corpus callosum; GCC, genu of corpus callosum; PIC, posterior limb of internal capsule; LN, lenticular nucleus; CR, corona radiate; CS, centrum semiovale; MMSE, mini-mental state examination; MoCA, Montreal cognitive assessment scale; HDSR, Hasegawa dementia scale revised; CDR, clinical dementia rating scale; DST digit span test; VFT, verbal fluency test; FAB, frontal assessment battery; TMTA, trail making test A; RAVLT, Rey auditory verbal learning test (immediate recall/short-term delayed recall/long-term delayed recall/recognition); NPI-Q, neuropsychiatric inventory-questionnaire (NPI-Q1: the score of patient, NPI-Q2: the score of caregiver); HAMA, Hamilton anxiety scale; HAMD, Hamilton depression scale; ADL, activity of daily living scale. *p < 0.05, **p < 0.01. Bold data (0.6–0.8), indicating high-intensity correlation.