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. 2022 Aug 16;14(16):3357. doi: 10.3390/nu14163357

Figure 1.

Figure 1

Untargeted metabolomic analysis of terminal and intermediate hair follicles from FPHL patients. (a) Number of metabolites identified by UPLC-MS analysis in n = 3−6 pooled terminal and n = 5–6 pooled intermediate/miniaturized hair follicles from the occipital and parietal scalp from n = 3 Female Pattern Hair Loss (FPHL) donors. n = 81 metabolites were identified in all three FPHL patients, n = 16 metabolites were commonly identified only in FPHL patients 1 and 2, n = 15 were commonly identified only in FPHL patients 2 and 3, and n = 29 were commonly identified only in FPHL patients 1 and 3. (b) Relative expression of the n = 141 metabolites identified in at least two FPHL patients. Heat maps show the Log2 fold change (FC) expression between intermediate/miniaturized and terminal hair follicles (i-m/t) in the occipital (OCC) and parietal (PAR) scalp region of each FPHL patient (FPHL1, FPHL2, and FPHL3) and the Log2 fold change (FC) average expression from the n = 3 FPHL donors.