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CD8+ T-cell response against peptide 1 presented by HLA-B7 (A), CD4+ T-cell response against peptide 2 presented by HLA-DRB1 (B) and CD8+ T-cell response against peptide 3 presented by HLA-A2 (C) contained in the PLGA nanovaccine formulations obtained via the inline (purple) and probe (grey) sonication methods. Each dot represents the mean value of triplicate wells. Assays are performed with three different nanoparticle batches. (*) Significant p < 0.05.
