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Levels of plasma kynurenine (A), KYNA (B) and 5-HIAA (C) at baseline and 30, 60, 90 and 240 min after oral administration of either placebo or TRP (6 g) in healthy controls (HCs, n = 16) and people with schizophrenia (SZ, n = 22) (arrows). Data are the mean ± SEM. Kynurenine (p < 0.001), KYNA (p < 0.001) and 5-HIAA (p = 0.038) increased after TRP challenge in both groups. See text for further details.
