Table 1.

Cytotoxicity of Bis-PMSs 5 and 6 in normal and cancer cells. IC₅₀ (µmol/L) of Bis-PMSs 5 and 6 was determined in HF-P4 and BJ-hTERT human fibroblasts, BLM and A2058 human melanoma cells, H1299 human non-small cell lung cancer cells, human BT-20 breast cancer cells, human U251MG and mouse Gl261 glioblastoma cells and U2-OS human osteosarcoma cells.

Cell Lines	Bis-PMS 5		Bis-PMS 6
	Mean (µM)	SD	Mean (µM)	SD
HFP4	0.987	0.575	1.499	0.452
BJ-hTERT	1.660	0.038	1.218	0.442
BLM	0.300	0.117	1.419	0.486
A2058	0.287	0.109	0.636	0.359
H1299	2.755	0.063	0.169	0.031
BT-20	0.701	0.228	0.779	0.160
U2-OS	0.496	0.145	0.242	0.092
U251	0.719	0.219	0.505	0.020
Gl261	0.971	0.079	0.268	0.050