Table 4.
Frequencies of disease manifestations in ADPKD in clinical-reported studies compared with those in the Registry
| Data Source | Year | Self/ Clinical | Single/ Multicenter | Subjects | Family History of ADPKD, % | Urinary Tract Infections, % | Hypertension, % | Presence of Liver Cysts, % | History of Cerebral Aneurysm, % |
|---|---|---|---|---|---|---|---|---|---|
| ADPKD Registry | 2021 | Self | n/a | 1327 | 80 | 22 | 80 | 63 | 6 |
| Gabow (12) | 1992 | Clinical | Single | 580 | 44 | 70 | 49 | 21 | |
| Thong (13) | 2013 | Clinical | Single | 565 | 79 | 27 | 70 | 56 | 5 |
| Chen (14) | 2014 | Clinical | Single | 541 | 75 | 67 | 72 | ||
| Eriksson (15) | 2017 | Clinical | Multicenter | 266 | 65 | 26 | 5 |
Gabow clinical site was the University of Colorado in Denver. Thong clinical site was the Sheffield Kidney Institute in the United Kingdom. Chen clinical site was Changzheng Hospital in Shanghai, People’s Republic of China. Eriksson was at nine clinics (four in Denmark, one in Finland, two in Norway, and two in Sweden). ADPKD, autosomal dominant polycystic kidney disease.