Table 3.
Clinical characteristics on the basis of quartiles of proportion of dialysis with high UFR
| Characteristic | Q1, N=321 | Q2, N=207 | Q3, N=261 | Q4, N=261 |
|---|---|---|---|---|
| Age, yr | 59 (49–67) | 60 (49–67) | 60 (50–71) | 58 (44–66) |
| Sex | ||||
| Women | 146 (45) | 99 (48) | 107 (41) | 118 (45) |
| Men | 175 (55) | 108 (52) | 154 (59) | 143 (55) |
| Race | ||||
| Black | 289 (90) | 196 (95) | 237 (91) | 236 (90) |
| White | 28 (9) | 11 (5) | 16 (6.1) | 15 (6) |
| Native Hawaiian | 0 (0) | 0 (0) | 1 (0.4) | 2 (0.8) |
| Asian | 4 (1) | 0 (0) | 7 (3) | 8 (3) |
| Access at 3 months | ||||
| Fistula or graft | 146 (45) | 86 (42) | 112 (43) | 94 (36) |
| Catheter | 175 (55) | 121 (58) | 149 (57) | 167 (64) |
| Best access | ||||
| Fistula or graft | 291 (91) | 181 (87) | 224 (86) | 219 (84) |
| Catheter | 30 (9) | 26 (13) | 37 (14) | 42 (16) |
| Diabetes | 193 (60) | 118 (57) | 141 (54) | 132 (51) |
| Viral diseasea | 33 (10) | 27 (13) | 35 (13) | 43 (16) |
| Malignancy | 6 (2) | 4 (2) | 7 (3) | 7 (3) |
| Lung disease | 8 (3) | 5 (2) | 5 (2) | 6 (2) |
| Liver disease | 4 (1) | 1 (0.5) | 3 (1) | 1 (0.4) |
| Cerebrovascular accidentb | 20 (6) | 18 (9) | 16 (6) | 15 (6) |
| Peripheral vascular diseasec | 21 (7) | 10 (4.8%) | 21 (8) | 22 (8) |
| Coronary artery diseased | 45 (14) | 24 (12) | 28 (11) | 28 (11) |
| Congestive heart failuree | 99 (31) | 58 (28) | 83 (32) | 57 (22) |
| Arrhythmiaf | 21 (7) | 13 (6) | 18 (7) | 10 (4) |
| Valvular diseaseg | 4 (1%) | 2 (1) | 3 (1) | 1 (0.4) |
| Dialysis count, % | 11,208 (31) | 7212 (20) | 8988 (25) | 8764 (24) |
| UFR, ml/kg per hour | 4.7 (3.7–5.6) | 5.8 (4.6–6.9) | 7.1 (6.1–0.2) | 9.8 (8.7–11.3) |
| Ultrafiltration, L/dialysis | 1.5 (1.2–2) | 1.6 (1.1–2.2) | 1.8 (1.4–2.2) | 2.2 (1.7–2.6) |
| % HD with high UFR | 0 (0–0) | 3 (3–3) | 8 (6–10) | 26 (18–36) |
| % Patients with high UFR | 0 | 0 | 0 | 10 |
| Weight, kg | 92 (79–111) | 82 (67–96) | 72 (64–83) | 66 (57–74) |
| Dialysis time, min | 210 (206–225) | 209 (203–224) | 209 (202–214) | 206 (196–210) |
| KtV | 1.3 (1.2–1.5) | 1.3 (1.2–1.6) | 1.4 (1.23–1.53) | 1.4 (1.25–1.64) |
| Mean arterial pressure pre | 105 (96–113) | 106 (96–113) | 105 (95–113) | 107 (98–117) |
| Mean arterial pressure post | 101 (94–108) | 100 (94–108) | 101 (93–109) | 105 (96–112) |
| % HD with hypotensionh | 3 | 3 | 5 | 3 |
| Albumin, g/dl | 3.9 (3.6–4.1) | 3.8 (3.5–4.1) | 3.8 (3.5–4) | 3.8 (3.5–4.1) |
| Normalized protein catabolic rate | 0.9 (0.8–1.1) | 0.9 (0.8–1) | 0.9 (0.8–1.1) | 1 (0.8–1.2) |
| Calcium, mg/dl | 9 (8.5–9.3) | 8.9 (8.5–9.3) | 8.9 (8.4–9.2) | 8.8 (8.3–9.1) |
| Phosphorus, mg/dl | 4.9 (4.2–5.5) | 4.8(4.1–5.7) | 4.8 (4.2–5.5) | 5.2 (4.4–5) |
| Parathyroid hormone, pg/ml | 408 (259–618) | 394 (263–594) | 377 (239–542) | 366 (233–597) |
| Hemoglobin, g/dl | 10.1 (9.3–11) | 10.1 (9.2–10.9) | 9.9 (8.9–10.7) | 9.8 (8.8–10.9) |
| Cholesterol, mg/dl | 148 (126–174) | 148 (124–174) | 141 (117–172) | 146 (124–171) |
| Potassium, mEq/L | 4.2 (3.9–4.5) | 4.2 (3.8–4.5) | 4.2 (4–4.5) | 4.3 (4–4.6) |
Data shown as median (interquartile range) or n (%). UFR, ultrafiltration rate; HD, hemodialysis.
a
Hepatitis B, hepatitis C, or HIV.
b
Ischemic or hemorrhagic stroke.
c
Claudication, documented arterial insufficiency, and/or leg amputation.
d
History of coronary artery surgery, myocardial infarction, or coronary angina.
e
Systolic or diastolic.
f
Atrial or ventricular arrythmias, bradycardia, and/or pacemaker presence.
g
Significant valvular abnormality or history of valvular surgery and/or replacement.
h
Drop from pre-HD systolic BP ≥160 to <100 mm Hg or any drop to <90 mm Hg during dialysis session.