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. 2022 Aug 26;17(8):e0273013. doi: 10.1371/journal.pone.0273013

Fig 4. Clostridioides difficile PaLoc tcdC gene structure.

Fig 4

(A) A Partial multiple alignment of the tcdC gene. The C→A mutation of the RT883 and 884 isolates at position 191 that generates a “TAA” stop codon is highlighted by a red arrow, while the point deletion that resulted in a frameshift in 885 is highlighted by an orange arrow. (C) Amino acid sequences encoded by the tcdC genes in RT883, 884, and 885 are shown; the stop codons are represented by red asterisks. Positions after the first stop codons are represented in gray. C) Multiple alignment of the tcdC gene in RT883, RT884 and RT885. Asterisks at the bottom denotes conserved sequences in all isolates. The orange arrow represents the frameshift position in RT885.