Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 9;226(3):407–419. doi: 10.1093/infdis/jiaa325

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 6. — HULC levels in human liver and blood. A, Total RNA was isolated from liver samples of 19 patients at pre– and post–hepatitis C virus (HCV) eradication. HULC and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) RNA levels in human liver were quantified by reverse-transcription quantitative polymerase chain reaction (RT-qPCR). HULC levels were normalized to those of GAPDH RNA. Differences in HULC levels between pre- and posteradication were analyzed by a paired t test (left) and Mann–Whitney test (right). The left panel shows paired levels in individual patients and the right panel shows nonpaired levels for all patients. The bars show geometric mean with geometric standard deviation (SD). B, Total RNA was isolated from blood samples of 213 patients at pre- and post-HCV eradication. HULC levels in blood per microliter were quantified by RT-qPCR. The left panel shows paired levels in individual patients and the right panel shows nonpaired levels for all patients. The bars show geometric mean with geometric SD. Differences in HULC levels between pre- and post-eradication were analyzed by a paired t test (left) and Mann–Whitney test (right). C, Total RNA was isolated from blood samples of 15 patients in whom HCV eradication was unsuccessful and 213 patients with successful HCV eradication at postantiviral treatment. HULC levels in blood per microliter were quantified by RT-qPCR. The bars show geometric mean with geometric SD. Differences in HULC levels between HCV-eradicated and HCV-noneradicated patients were analyzed by Mann–Whitney test. *P < .05, **P < .01, ***P < .001.