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. 2022 Aug 12;14(15):6047–6065. doi: 10.18632/aging.204216

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Copyright: © 2022 Ngwa et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Microglial phagocytosis by flow cytometry performed on IRF4 CKO stroke and sham mice. Quantification data are presented as mean percentage of bead⁺ microglia. (A, B) Fluorescence intensity plots for IRF4 KO and flox microglia exposed to FITC fluorescent bioparticles. (C) Percentage fluorescence of phagocytosis in IRF4 CKO vs. flox sham and stroke microglia; and (D) comparative quantified data for the ratio of IRF4 CKO stk/shm vs. IRF4 flox stk/shm in (C). n = 4 to 5 per sham and 6 to 7 per stroke group; *P < 0.0500, **P < 0.0010, ***P < 0.0001.