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. 2022 Aug 12;13:913659. doi: 10.3389/fgene.2022.913659

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Copyright © 2022 Zhang, Luo and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FN1 mRNA expression in breast cancer and other different types of human cancers. (A) Significantly different FN1 mRNA expression in 12 tumor types in the TIMER database. *p < 0.05; **p < 0.01; ***p < 0.001. (B) Significantly higher FN1 mRNA expression in breast cancer tissue compared with normal breast tissue in the GSCA database. FDR, false discovery rate. (C) The association of FN1 expression with different clinical characteristics by the Sankey diagram based on the TCGA BRCA data. Age: 1 represents ≤51 (years), 2 represents >51 (years); Gender: 1 represents female, 2 represents male; Subtype: 1 represents luminal, 2 represents HER2+, 3 represents triple-negative; OS status: 0 represents living; 1 represents deceased; DFS status: 0 represents disease-free; 1 represents recurred; FN1: 1 represents low FN1 mRNA expression, 2 represents high FN1 mRNA expression. OS, overall survival; DFS, disease-free survival.