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. 2022 Aug 12;12:978006. doi: 10.3389/fonc.2022.978006

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Copyright © 2022 Chen, Zhang, Zhou, Ye, Luo, Yang, Fang and Tang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic validation for the HMOX1-mediated metastasis regulatory network in LUAD. (A) Volcano plots showing the differentially expressed proteins between the high and low HMOX1 groups. (B) GO enrichment for the differentially expressed proteins. (C) The difference in EMT, mitochondrial complex, and macrophage between the high, medium, and low HMOX1 groups. (D) Correlation between HMOX1 and EMT, mitochondrial complex, macrophage. (E) The difference in proteins of the HMOX1 regulatory network among high, medium, and low HMOX1 groups. (F) Correlation among proteins of the HMOX1 regulatory network *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.