Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 28;36(9):2233–2241. doi: 10.1038/s41375-022-01656-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Fig. 4 — a Sorting protocol for CLL cells according to reciprocal and intermediate expression of CXCR4 and CD5. Gates were set to collect 15% of events within each subpopulation: CXCR4_lo/ CD5_hi (red arrow), CXCR4_int/CD5_int (blue arrow), and CXCR4_hi/CD5_lo (green arrow). b Deuterium enrichment curves of sorted CLL cells: CXCR4_loCD5_hi (red circles), CXCR4_intCD5_int (blue squares), and CXCR4_hiCD5_lo (green triangles). Results are shown from 7 subjects (K2, K3, K4, K5, K6, K9, and K10), expressed as fraction of new cells (F %) normalised to one day’s labeling; error bars represent the standard deviation of ≥4 replicate measurements by GC-MS. The F scale varies between subjects to best represent deuterium enrichment. Time represents days post-labeling. Note that K5 had a dual population of CLL cells.