Table 3.

The mean absolute error (MAE) and R-squared (R²) obtained with linear predictions with leave-one-out validation. Conventional whole brain metrics and established tract-specific metrics were used to predict processing speed and memory scores. Bold indicates the best prediction for each cognitive domain

N = 102 subjects		Processing speed		Memory
Model	Predictors	MAE	R2	MAE	R2
Conventional whole brain metrics
1	Age + sex + education	0.63	0.27	0.68	0.26
2	1 + lesion markers + BPF	0.63	0.30	0.70	0.25
3a	2 + MD	0.57	0.38	0.70	0.25
3b	2 + FA	0.63	0.31	0.69	0.25
3c	2 + PSMD	0.62	0.29	0.69	0.26