Figure 5.

Collagenase induced hemorrhage in the striatum observed with 3DULM in the early phase. (a) 3D renderings before, and 1h30 after stroke’s induction, and the day after (Supplementary Video S2). (b) Sagittal and coronal slices of 600 µm with velocity rendering at different timepoints. Hemorrhagic core wrapped with a white dotted line. $V_{\mathit{max}}=30\mathrm{mm}/\mathrm{s}$. Upward flow: red, downward flows: blue. (c) T2* MRI at D + 1. Scale bar: 2 mm. Yellow arrow targets the hemorrhagic core. (d) Projection of the selected ROI in the cortex and thalamus as a reference. (e) MDI values for the ROI inside the hemorrhagic core and the reference normalized with the baseline. (Results of the analysis of 1 animal over 5.) Figures were created with (a) Amira 2019.4 (https://www.thermofisher.com/amira-avizo), (b–e) MatLab 2019a (https://www.mathworks.com/products/matlab).