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. 2022 Aug 26;12:14607. doi: 10.1038/s41598-022-18025-x

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© The Author(s) 2022, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison between ischemic and hemorrhagic models. Variation of the MDI normalized prior onset (t−) for each ROI in the ischemic (a) and hemorrhagic (b) stroke and reference ROIs. Ratios between the ischemic (c) and hemorrhagic (d) strokes ROI and the reference region. (e) Normalized MDI ratio of the lesion site and the reference region, compared to the baseline (t-). All animals were pooled for baseline ratio in cortex and striatum (n = 9). Student t-test with equal variance (f) Volume renderings of ischemic (left) and hemorrhagic (right) strokes 30 min after onset. Scale bar 2 mm. Figures were created with (a–e) MatLab 2019a (https://www.mathworks.com/products/matlab), (f) Amira 2019.4 (https://www.thermofisher.com/amira-avizo).