Table 2.

Cox regression overall survival analysis.

	Univariate analysis			Multivariate analysis
	HR	95% CI	p value	HR	95% CI	p value
ECOG	0.96	0.59–1.56	0.869	1.16	0.67–2.00	0.548
Age > 65	0.81	0.50–1.31	0.394	0.79	0.47–1.33	0.376
Smoking history	0.72	0.42–1.48	0.463	0.80	0.35–1.79	0.580
Gender	1.81	1.10–2.98	0.019	1.76	0.91–3.40	0.090
Brain metastasis	1.14	0.69–1.87	0.620	1.22	0.72–2.06	0.463
Liver metastasis	0.96	0.52–1.75	0.882	1.08	0.58–2.03	0.805
Anti-angiogenesis	0.51	0.29–0.88	0.016	0.50	0.27–0.91	0.025
T790M	0.98	0.58–1.64	0.932	1.19	0.68–2.08	0.548