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. 2022 Aug 9;7(4):415–423. doi: 10.1089/can.2020.0119

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Copyright 2022, Mary Ann Liebert, Inc., publishers

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FIG. 1. — Effects of THC treatment for 3 days following CCI. Both the THC-treated group (n=6 mice) and vehicle-treated group (n=6 mice) were trained to run on a rotometer before undergoing CCI. After CCI, treatment with THC 3 mg/kg for 3 days resulted in a time-dependent recovery of motor function. Two-way ANOVA testing showed that both treatment (THC vs. vehicle) and time (days) after CCI contributed significantly to total variance (p<0.005). Sidak's correction for multiple comparisons revealed that THC significantly improved time on the rotometer compared to vehicle treatment on day 14 (p=0.029). ANOVA, analysis of variance; CCI, controlled cortical impact; THC, tetrahydrocannabinol.