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. 2022 Aug 11;20:4464–4472. doi: 10.1016/j.csbj.2022.08.016

Table 1.

Rab proteins and their effectors in endocytic transport.

Rab Effector Function References
Rab4 AKAP10/D-AKAP2 Transferrin receptor recycling [31]
CD2AP/CMS Endosome morphology and lysosomal degradation [25]
GRASP-1 Maturation of recycling endosome [50]
NDRG1 Recycling of E-cadherin [59]
Rip11/RCP Endosomal recycling [71]
Rabaptin5/RABEP1/Rbpt5 Endosome maturation [61]
RUFY1/Rabip4s Endocytic recycling [135]
ZFYVE20/Rabenosyn5 Endocytosis [126]
Rab5 Rabaptin5/RABEP1/Rbpt5 Endosome maturation [61]
ZFYVE20/Rabenosyn5 PI3P level on early endosomes [86]
Mon1/SAND-1 Early-to-late endosomes conversion [63]
EEA1/EEA-1 Endosomal membrane fusion [40]
Erbin/LET-413 RAB-10 activity [74]
Rab7 RILP Late endosome to lysosome trafficking [11]
FYCO1 Microtubule plus end-directed vesicle transport [95]
Retromer complex(Vps26, Vps29, and Vps35) Late endosome to Golgi trafficking [107]
Rabring7 EGF receptor degradation [108]
Rab9 TIP47 Receptor recruitment [13]
p40 Endosome-to-TGN transport [28]
Nde1 Interaction between late endosomes and dynein [154]
RUTBC1/2/TBC-8 N/A [90], [91]
GCC185 Endosome-to-TGN transport [102]
Rab10 TBC-2 Endocytic recycling [76]
ACAPs/CNT-1 Endocytic recycling [120]
EHBP1/EHBP-1 Endocytic recycling [118], [136]
SEC16A Insulin-stimulated GLUT4 trafficking [7]
Rab11 Rab11BP/Rabphilin-11 Endocytic recycling [78], [146]
Rip11/RCP Endosomal recycling [71]
myosin Vb Rab11-FIP2-dependent recycling [46], [85]
Rip11/pp75 Apical recycling [101]
Rab11-FIP1/FIPP-1 Rab11-dependent recycling [46]
Nuf/Rab11-FIP3/Arfophilin2 Membrane traffic in cytokinesis [12]
Rab11-FIP4/RFIP-1 Membrane traffic in cytokinesis [33]
Sec15 Exocyst function in recycling [151]
Rab35 OCRL/OCRL-1 Membrane traffic in cytokinesis [15]
Fascin Actin Bundling during cell migration [147]
RUSC/NESCA Rab35 activity [35]
MICAL-L1 Membrane traffic during neurite outgrowth [68]
centaurin-β2/ACAP2/CNT-1 Membrane traffic during neurite outgrowth [67]