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. 2020 Mar 30;2(5):1774–1791. doi: 10.1039/d0na00051e

Synthetic protocols of Ru-cNMs and their critical analysis against 12 principles of green chemistry as stated by Paul Anastas.

Name of synthetic protocol Sol–gel immobilization Adsorption-reduction Bio-reduction Core–shell synthesis
Number of reports for Ru-cNMs 8 1 6 3
Synthetic protocol Metal solution is reduced to metal sol followed by its loading over a suitable substrate Metal ions are incorporated over the substrate and then reduced by a suitable reducing agent Metal electrolyte is reduced and stabilized by bioextracts, biomass, biologically derived compounds In vitro synthesized metal particles reduce the metal ions, using reductive physiology of a live cell
Reducing agent (bioextract) Reducing metabolites Reducing metabolites Reducing metabolites Enzymatic reduction
Capping agent (bioextract) Secondary metabolites Secondary metabolites Secondary metabolites Protein residue
Solvent medium Aqueous Aqueous Aqueous/non-aqueous Aqueous
Energy consumption Temperature, stirring Temperature, stirring Calcination may/may not Incubation
Substrate employed CNT, AC, ITO-Gs, NiF, biomass CB
Activity of Ru-cNMs High surface activity Low surface activity Catalysis and bioactivity Catalysis
Principles of green protocol:
(1) Prevention graphic file with name d0na00051e-u1.jpg graphic file with name d0na00051e-u2.jpg graphic file with name d0na00051e-u3.jpg graphic file with name d0na00051e-u4.jpg
(2) Atom economy graphic file with name d0na00051e-u5.jpg graphic file with name d0na00051e-u6.jpg graphic file with name d0na00051e-u7.jpg graphic file with name d0na00051e-u8.jpg
(3) Less hazardous chemical synthesis graphic file with name d0na00051e-u9.jpg graphic file with name d0na00051e-u10.jpg graphic file with name d0na00051e-u11.jpg graphic file with name d0na00051e-u12.jpg
(4) Designing safer chemicals graphic file with name d0na00051e-u13.jpg graphic file with name d0na00051e-u14.jpg graphic file with name d0na00051e-u15.jpg graphic file with name d0na00051e-u16.jpg
(5) Safer solvents graphic file with name d0na00051e-u17.jpg graphic file with name d0na00051e-u18.jpg graphic file with name d0na00051e-u19.jpg graphic file with name d0na00051e-u20.jpg
(6) Design for energy efficiency graphic file with name d0na00051e-u21.jpg graphic file with name d0na00051e-u22.jpg graphic file with name d0na00051e-u23.jpg graphic file with name d0na00051e-u24.jpg
(7) Use of renewable feedstocks graphic file with name d0na00051e-u25.jpg graphic file with name d0na00051e-u26.jpg graphic file with name d0na00051e-u27.jpg graphic file with name d0na00051e-u28.jpg
(8) Reduce derivatives graphic file with name d0na00051e-u29.jpg graphic file with name d0na00051e-u30.jpg graphic file with name d0na00051e-u31.jpg graphic file with name d0na00051e-u32.jpg
(9) Catalysis graphic file with name d0na00051e-u33.jpg graphic file with name d0na00051e-u34.jpg graphic file with name d0na00051e-u35.jpg graphic file with name d0na00051e-u36.jpg
(10) Design for degradation graphic file with name d0na00051e-u37.jpg graphic file with name d0na00051e-u38.jpg graphic file with name d0na00051e-u39.jpg graphic file with name d0na00051e-u40.jpg
(11) Real-time analysis for pollution prevention graphic file with name d0na00051e-u41.jpg graphic file with name d0na00051e-u42.jpg graphic file with name d0na00051e-u43.jpg graphic file with name d0na00051e-u44.jpg
(12) Inherently safer chemistry for accident prevention graphic file with name d0na00051e-u45.jpg graphic file with name d0na00051e-u46.jpg graphic file with name d0na00051e-u47.jpg graphic file with name d0na00051e-u48.jpg
Number of principles followed 7 10 11 7